Best B2B eCommerce Agencies
We scored and ranked the top 50 agencies specializing in B2B eCommerce across all major eCommerce platforms, using verifiable data signals and editorial review.
Top Agencies
Atwix

Atwix is an award-winning e-commerce agency offering comprehensive solutions for B2B and complex e-commerce implementations. The team specializes in Shopware, Shopify Plus, Bigcommerce and Adobe Commerce platform development. Services include design, build, and optimization of e-commerce solutions, technical integrations, and complete digital transformation support. The agency also offers consulting services covering website architecture, security and SEO auditing, and strategic e-commerce roadmap development. Atwix provides ongoing proactive support to help merchants scale faster and with greater technical reliability and care. Atwix is a TOP #1 contributor to Magento and Adobe Commerce core code since 2018.
Brilliance Business Solutions

Brilliance Business Solutions serves manufacturers and distributors with specialized B2B digital commerce expertise. The firm provides tailored eCommerce implementations on Shopify and BigCommerce platforms, with deep experience in integrating complex data systems and streamlining operations. Based on available information, Brilliance offers comprehensive support including strategy consultation, platform selection, system integration with existing back-office applications, and ongoing optimization to drive growth and efficiency.
Luminos Labs

Luminos Labs is a digital commerce implementation specialist focusing on complex Shopify Plus and enterprise-level builds. They architect, design, and integrate solutions that connect front-end customer experiences with back-office systems. The agency works with B2B businesses and multi-entity brands requiring sophisticated, integrated platforms.
Reply Group

Reply Group is an eCommerce agency focused on delivering scalable commerce solutions across Shopify Plus, Adobe Commerce, and B2B platforms. The firm specializes in building hyper-personalized customer experiences through data-driven strategies, leveraging Adobe Experience Cloud technologies. They emphasize an AI-infused approach to accelerate implementation and reduce operational costs, with core competencies in content supply chain optimization, unified customer experience delivery, and B2B go-to-market orchestration. Founded in 2008 and built as a certified Adobe partner, the company has deep expertise in experience management, asset optimization, and omnichannel engagement strategies.
Silk Commerce

Silk Commerce is a full-service digital agency specializing in B2B commerce and B2C eCommerce. The firm serves B2B manufacturers, distributors, and direct-to-consumer brands, offering services from business consulting and custom development to design and optimization. Silk works across multiple leading eCommerce platforms and emphasizes helping businesses achieve digital transformation and revenue growth through comprehensive commerce strategies.
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About B2B eCommerce
B2B eCommerce demands a different skill set from consumer-facing storefronts. Agencies that excel in this space understand complex pricing structures, bulk ordering workflows, custom catalogs, quote-based purchasing, and integration with ERP and procurement systems. The best B2B agencies bring experience across multiple platforms and verticals — from industrial manufacturing and wholesale distribution to SaaS-enabled commerce.
Our B2B eCommerce ranking evaluates agencies on signals that matter most for business buyers: depth of platform partnerships, company maturity, verified client reviews, growth trajectory, and demonstrated B2B expertise in their portfolio and service descriptions. Every agency on this list has been independently scored using public, verifiable data — no pay-to-play or self-reported metrics.